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doi:10.1016/j.cell.2017.02.031

If bilirubin rises alongside transaminases (Hy's Law criteria), this is a serious drug-induced liver injury signal requiring specialist input

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8 OnabotulinumtoxinA may also interfere with the release of other neurotransmitters involved in pain mediation, including substance P, calcitonin-related gene peptide, dopamine, norepinephrine, enkephalin, and neurokinin A